Wham clusters each of the candidate breakpoints and rounds their positions to the closest tenth base pair. The position with the highest read assistance is claimed. In the event the delicate-clipped consensus sequence may be aligned for the putative breakpoint location using the Smith-Waterman algorithm, the breakpoint is further refined to The pla

Wham is suitable for paired-conclude Illumina libraries with conventional insert measurements (~300bp-500bp). Wham integrates mate-pair mapping, split read through mapping, tender-clipping, different alignment and consensus sequence primarily based evidence to predict SV breakpoints with one-nucleotide accuracy. Wham generates a combined pileup (ca

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